The Farese and Walther laboratory studies how cells store metabolic energy in the form of lipids.
Read MoreThe Farese and Walther laboratory studies how cells store metabolic energy in the form of lipids.
Read MoreWe study metabolism of the endo-lysosomal system, and its relationship to cancer and neurodegenertive disease (such as FTD, ALS, Alzheimers).
Read MoreWe employ techniques such as mass spectrometry, genome-perturbations screens, and high-content microcopy to generate hypotheses or models for biological processes.
Read MoreLecture #3: Thursday, January 18, 2024 The Skinny on Fat: Mechanisms and Physiology of Lipid Storage Robert Farese, MD & Tobias Walther, PhD
Read MoreRobert V. Farese, MD is a Professor of Genetics and Complex Diseases at Harvard T.H. Chan School of Public Health. He talks about about Integrity and excellence in communication are important to his research brand. Bob also shares a unique organizational structure for running a lab. Music from Podington Bear. Use with Creative Commons Attribution-NonCommercial 3.0 License.
Read MoreBob and Tobi's iBiology lectures on the basic mechanism of lipid droplet biology
Read MoreBasic science is at the heart of many of our greatest health advances. And in this week's episode we speak with two scientists who are asking fundamental questions about how our bodies work. The answers could help crack the secrets of diseases ranging from diabetes to dementia.
Read MoreCo-Principal Investigator
Member, Cell Biology Program, SKI Alfred P. Sloan Chair, MSKCC Professor, Weill Cornell
Co-Principal Investigator
Program Chair, Cell Biology Program, SKI Enid A. Haupt Chair, MSKCC Professor, Weill Cornell Investigator, Howard Hughes Medical Institute (HHMI)
Visiting Investigator (HHMI)
I am building a software platform for analyzing and storing lipidomics data.
Scientific Research Lead (SKI)
My background is in analytical chemistry and I apply my expertise to better understand the links between lipid metabolism and common diseases, such as neurodegeneration or cancer.
Research Associate
I am from Spain and love outdoors activities and sports. I came to the Farese and Walther lab driven by curiosity to mechanistically understand lipid droplets. Now, I work on understanding how proteins organize lipid droplet formation, and how proteins target lipid droplets.
Senior Research Specialist (HHMI)
I have some 20 years of experience in life science industry. Currently, I am working on novel approaches to modulate metabolism and to target cancer.
Postdoctoral Fellow
I am a cancer biologist and study pathways of lipid metabolism in tumorgenesis
Graduate Student
I am studying lysosomal biology and lipid turnover
Postdoctoral Fellow
I am a biochemist, structural and cell biologist interested in mechanisms of lipid metabolism.
Research Technician (HHMI)
I have an undergraduate degree in Biology and Society and am interested in cancer therapeutics. When not running cell based assays, I enjoy experimenting with new coffee flavors.
Postdoctoral Fellow (joint with W. Harper lab at Harvard)
I work on the mechanisms that target proteins to lipid droplets
Postdoctoral Fellow
I am a HFSP postdoc fellow in the lab. I graduated from IISER-Pune in 2021 and joined our lab to study lysosomal lipid metabolism in context to neuro-immune diseases. I am broadly interested in understanding various aspects of lipid physiology in the development and maintenance of central nervous system.
Lab Manager
I studied neuroscience during my graduate career but now I am the peacemaker, also known as the Lab Manager of the Farese and Walther Lab. When I'm not placing orders or re-organizing the lab, I love to listen to Beyoncé, Twice, and Bad Bunny.
Research Specialist (HHMI)
I am an interdisciplinary expert in biology and optics in the F&W lab. I use Lattice light-sheet microscope to study lipid droplet biogenesis.
Postdoctoral Fellow
I am interested in the pathways of triglyceride synthesis. Now I am working on the feedback regulation of lipogenesis
Research Technician
I have an undergraduate degree in Biophysics. I’m deeply involved in both the operational side of our mass spectrometer and in the analytical side of lipidomics. In my spare time I like playing chess and climbing rocks.
Postdoctoral Fellow
I studied the accumulation and release of protein aggregates from lysosomes in neurodegenerative diseases during my PhD. With the lab’s expertise on lipid metabolism, I am interested in studying the accumulation of lipids in neurodegenerative diseases.
Research Specialist (HHMI)
I have completed training specializing in triglyceride storage and physiology in adipose tissue. My current research focuses on understanding brain lipid metabolism in normal physiology and in neurodegenerative diseases.
Assistant to Chair
As scientist, my findings include: 1) RNA binding protein, ZBP1, play a role in breast cancer progression to metastasis. 2) Traumatic stress altered expression of norepinephrine transporter in brain leading to hyperarousal features as seen in PTSD patients. 3) Neonatal opioid exposure led to differentially expressed genes in synapse development pathways, the GABAergic and myelin systems, and mitochondrial function. 4) I developed an intravital MBS-MCP method by which mRNAs can be visualized in specific cell types of the living mouse brain. As Assistant to Chair, I hope to leverage my scientific background to further propel scientific, business and healthcare administration.
Graduate Student
I graduated from Hamilton College with a B.A. in Biochemistry in 2023. I joined the Farese and Walther Lab in 2024 as a member of the BCMB program to study the trafficking of proteins to the lipid droplet. I enjoy running, biking, hiking with friends & drinking good coffee.
Senior Administrative Assistant
I hold a bachelor’s degree in biomedical informatics from CUNY New York City College of Technology, with extensive experience in drug discovery and laboratory research. Combining my scientific background with strong organizational and administrative skills, I am eager to support Dr. Farese, Dr. Walther, and the lab team as the Senior Administrative Assistant in advancing their research and projects. Outside of work, I enjoy playing electric guitar, listening to metal music, and playing video games with friends.
Research Scholar
I studied how lysosomal membrane resilience is regulated by ESCRT machinery during my Ph.D. I am broadly interested in the cell biology of lysosomes and lipid droplets.
Undergraduate Researcher
I am working on the biochemistry of lipid synthesis